BAFF-R(CD268)是B細(xì)胞存活的關(guān)鍵受體,在其成熟與維持過程中起重要作用?寺】贵w9B9被廣泛用于阻斷小鼠體內(nèi)的BAFF-R功能,助力研究人員深入探究B細(xì)胞存活機(jī)制、對BAFF-R信號傳導(dǎo)的依賴性,以及對狼瘡和類風(fēng)濕關(guān)節(jié)炎等自身免疫性疾病的影響。InVivoMAb抗小鼠BAFF-R(克隆9B9)能為臨床前及轉(zhuǎn)化研究中表達(dá)BAFF-R的B細(xì)胞提供可靠的體內(nèi)級功能性靶向方案。
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特色產(chǎn)品:
InVivoMAb BAFF-R (CD268)
Pathway: B cell survival, maturation, autoimmunity, and cancer biology
Clone: 9B9
Species: Monkey
Isotype: Rat IgG2b, κ
Target: BAFF-R (CD268)
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Comprehensive B Cell and Autoimmunity Research 其他關(guān)鍵靶標(biāo)
CD20
Application:B cell depletion
Species available: Human, Monkey, Mouse
BAFF/BAFF-R
Application:BAFF pathway in B cell biology
Species available:Human, Monkey, mouse
CD19
Application:Total B cell quantification
Species available:Human, Mouse